pharmaceutic researchers are one measure closer to making a pill that can overturn the symptom of type 2 diabetes . They published their research in the journalNature Chemical Biology .
Diabetes and its complications are a major publication within the United States and overseas . In 2012 , the American Diabetes Association report that 29.1 million Americans , or 9.3 percentage of the population , lived with diabetes .
Various factors , include eld and obesity , can stimulate a person ’s body to stop responding to the blood - moolah regulation hormone called insulin . Current drugs for type 2 diabetes employment by do away with glucose from a person ’s bloodstream . These prescriptions can help a great deal , but they ’re not a therapeutic , and the side effect can be nasty .
The authors of the new study question if they could come up to the trouble farther up in the pipeline by convince the soundbox to respond to insulin again . They created a compound that blocks the spill of a chemical called down in the mouth molecular weight protein tyrosine phosphatase ( LMPTP ) , an enzyme that ’s previously been implicated in insulin electric resistance .
They gave the drugs to a group of obese , diabetic computer mouse by oral fissure , once a day for four week , all the fourth dimension monitor the rodents ’ blood moolah and insulin resistance . In that short time , the animals ’ bodies began responding to insulin and their blood sugar began to steady . The mouse experienced no side effects .
The next step will be testing the drug in other beast , and then in people . conduct research worker Stephanie Stanford of the University of California , San Diego , is hopeful the pill ’s success will translate into the human body and trim back the pauperization for insulin injection and other drugs .
“ This could head to a new sanative scheme for treating case 2 diabetes , ” shetoldNew Scientist .
