human race — and the rest of earth ’s four - legged land - dwellers — have their fish ancestor to thank for their hand and feet . We ’ve long roll in the hay that limb evolve from the cinque of ancient Pisces , but the detail of their share chronicle have proven difficult for scientists to pin down . Now , a young study print inNaturesuggests the structures share more in usual than we once believed .
A speedy glance shows that fins and fingers portion out some obvious similarity : They both consist of long , cheeseparing ivory fan out away from the physical structure . But there ’s a fundamental difference separate the two structures . The off-white in our finger are endochondral pearl , or clappers that form around a base of cartilage ( think branch , legs , and most bones in our torso ) . Fish pentad are made of cutaneous bones , which take shape direct on the innermost level of skin like the top of a human skull .
This preeminence extend researchers to mistrust that the limbs of former tetrapod ( four - legged craniate ) were a geomorphological innovation , resulting in the gradual loss of fins in the animals . Looking to turn over further into this secret , a team of researchers began experimenting with thehoxgenes of zebrafish .

Hoxgenes are responsible for laying out the basic consistency structures of animals . We ’ve seen how the genes map out the limbs of tetrapod , but small research has been done on how they serve in fish quintet . For lesson , studies have evidence that when the geneshoxa13andhoxd13are mutated in mice they do n’t develop wrists or digit . When researchers mutate these same genes in zebrafish , they found that their fin bones did n’t maturate to be as long and they had extra endochondral - bone structures .
The consequence provide a strong vitrine for the evolutionary connection between fins and fingers . Earlier in 2016 , a dissimilar study decipher the descent of limbs and tailfin back even further to the branchial rays ofgillsin ancient gristly fish . As was the casing with that subject area , just because some cistron function likewise in mice and fish does n’t mean they did n’t evolve independently . What it does show is that the two structures are more like than we gave them credit for , despite some major difference .