magician do n’t needs generate superstar in the humankind of Harry Potter . Although two witching parents or one magical parent and one non - charming parent usually results in a magic - wielding materialization , you ofttimes get characters like Hermione , who have two non - charming parent , and sometimes squibs like Mr. Filch , hoi polloi who ca n’t wield thaumaturgy despite being born to a crone and a adept . So how is the wizarding gene passed down ?
JK Rowling has claim that the wizardly gene is dominant , but that ’s pass on many fan unsatisfied . If it ’s rife , how come neither of Hermione ’s parents possess magical abilities ? thrower fanAndrea Klenotiz decided to hear applying her knowledge of genetic science to Rowling ’s domain , and take she has total up with a scenario for a dominant magic gene that account for squibs and Muggle - borns that goes beyond Punnett square toes . She set off :
I show your argument that the wizarding factor is dominant . I have heard unfavorable judgment that this does not explain muggle - Born , squib , or the unfluctuating hereditary pattern pattern of magical abilities ; but I got your back . witching power could be explained by a single autosomal prevailing gene if it is triggered by an enlargement of trinucleotide repeats with non - Mendelian ratios of inheritance .
As we all know , DNA is made up of the nucleotide bases guanine , cytosine , adenine , and thymine . The sequence of these foundation decide what ware are transcribe . Trinucleotide repetition are one such potential sequence . Huntington ’s disease is a well - recognize transmitted condition . The Huntington ’s Disease Collaborative Research Group ( 1993 ) proved that the disease was due to CAG ( C - A - guanine ) trinucleotide repeats . The Huntington factor is prevalent and autosomal ( not yoke to sex chromosomes ) . Normally , a person has 11 to 34 CAG repeats in the cistron of involvement , which causes the written text of the normal huntingtin protein . Unfortunately , when an somebody has 42 to over 66 CAG repetition , the abnormal huntingtin protein transcribed causes serious symptom later in life . The huntingtin gene with an abnormal number of repetition shows dominant radiation diagram of inheritance over the huntingtin gene contain a normal turn of repeats . rent us involve that the factor determining magical ability contains trinucleotide repeat .
She uphold to present her line of reasoning for a prevalent magic gene , but then shifts geared wheel into other possibilities . Her favorite scenario for witching genetics ? That all magical ability stems from mutations to Muggle DNA . This leads into some interesting hypothesis about so - send for “ utter - blood ” family , whose blood might not be as Muggle - free as they suspected . Klenotiz also admit legion resourcefulness to back up her possibility , so that others may debate the finer peak of the wizard genome .
I sent this paper to JK Rowling explaining how the wizarding factor could be singular , autosomal , and rife … [Fus Ro Dah viaIt ’s Okay to be voguish ]
BooksGeneticsHarry PotterScience
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